immune cells – Communicable Diseases Research

Little to no expression of angiotensin-converting enzyme-2 on most human peripheral blood immune cells but highly expressed on tissue macrophages

Article

Published on 2023-02-012023-07-12
Journal: Cytometry. Part A : the journal of the Internation
[Category] SARS,

Comparative miRNA transcriptomics of macaques and mice reveals MYOC is an inhibitor for Cryptococcus neoformans invasion into the brain

원숭이와 생쥐의 비교 miRNA 전사체는 MYOC가 뇌로의 크립토코커스 네오포르만스 침입에 대한 억제제임을 보여줍니다

Article

Published on 2022-12-012022-09-11
Journal: Emerging Microbes & Infections
[Category] 유전자 메커니즘,

[키워드] AIDS Brain brain dissemination brains C. neoforman C. neoformans caused Central nervous system centric clinical samples clinically CNS Comparative Cryptococcal meningoencephalitis cryptococcosis Cryptococcus neoforman Cryptococcus neoformans cytoskeleton dissemination enhancer facilitate fungal Fungal infection help HIV/AIDS HIV/AIDS patient HIV/AIDS patients host-pathogen interactions hosts human pathogen Immune cell immune cells individuals Infection inhibitor inhibitors Invasion macaque Macrophage mechanism meningoencephalitis mice miRNA miRNA transcriptome. MYOC myocilin Pathogenic microorganisms pathway Patient patients with COVID-19 performed Prevalence regulated response reveal Transcriptome transcriptomics Trojan horse
[DOI] 10.1080/22221751.2022.2081619 PMC 바로가기 [Article Type] Article

Massive macroglossia, a rare side effect of COVID-19: clinical, histologic, and genomic findings in COVID-19-positive versus COVID-19-negative patients

Article

Published on 2022-12-012022-11-16
Journal: Oral and maxillofacial surgery
[Category] COVID19(2023년), SARS, 유전자 메커니즘,

Induction of pulmonary HLA-G expression by SARS-CoV-2 infection

Article

Published on 2022-11-052022-11-15
Journal: Cellular and Molecular Life Sciences
[Category] SARS, 치료기술, 치료제,

[키워드] accompanied Antigen Autopsy biopsies CD8 Cell changes in correlated distribution epithelial cell Evidence expressed expression expression level Frequency heart muscle HLA-G Hyperactivation Immune cell Immune cell infiltration immune cells Immune escape immune response induction information kidney leukocyte lung lung alveolar lung epithelia lung epithelial cell lung tissue Macrophage marker microRNA microRNA. miRNA miRNA expression modulating organs other organ patients protein expression SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections SARS-CoV-2 nucleocapsid SARS-CoV-2- SARS-CoV-2-infected patient specimen Spike protein surgical T cell responses T cells therapeutic target tissue tissues Treatment Tumor virus-infected cells while
[DOI] 10.1007/s00018-022-04592-9 PMC 바로가기

BNT162b2-induced neutralizing and non-neutralizing antibody functions against SARS-CoV-2 diminish with age

Article

Published on 2022-10-252022-11-15
Journal: Cell Reports
[Category] COVID19(2023년), SARS, 변종, 진단,

SARS-CoV-2 Variant-Specific Infectivity and Immune Profiles Are Detectable in a Humanized Lung Mouse Model

Article

Published on 2022-10-162022-11-15
Journal: Viruses
[Category] COVID19(2023년), SARS, 변종, 치료기술,

The impact of platelets on pulmonary microcirculation throughout COVID-19 and its persistent activating factors

Article

Published on 2022-09-282022-11-15
Journal: Frontiers in Immunology
[Category] 치료제,

[키워드] activate activating addition aggregation antiplatelet Blood coagulation factor complex convalescent COVID-19 COVID-19 patients disease severity disorders endothelial injury Factor Gas exchange hypercoagulability hypercoagulable hypercoagulable states Hypoxemia hypoxia immune cells impaired lung function impairment incidence Inflammation Inflammatory mediators inhibiting Intervention intrinsic involved Lung function manifestation marker microvesicle Microvesicles Mild Mortality Phosphatidylserine Platelet platelet activation Platelets promote PROTECT pulmonary permeability pulmonary vasculitis reactivity reducing resulting risk severe cases stages the disease therapy Thromboembolism thrombosis thrombosis. thrombotic event tissue Treatment vessel walls with COVID-19
[DOI] 10.3389/fimmu.2022.955654 PMC 바로가기

IFI44 is an immune evasion biomarker for SARS-CoV-2 and Staphylococcus aureus infection in patients with RA

Article

Published on 2022-09-152022-11-15
Journal: Frontiers in Immunology
[Category] SARS, 바이오마커, 유전자 메커니즘,

[키워드] 1,25-dihydroxy vitamin D3 activated acute respiratory syndrome analyses Analysis applied autoimmune conditions Bacteremia Bacterial Bacterial infection Bacterial infections Bioinformatics analysis Biomarker caused Cell cell membrane CIBERSORT conducted coronavirus COVID-19 Cytoscape database dataset datasets DEGs dendritic cell dendritic cells dendritic cells. differentially expressed differentially expressed gene disease DNA drug target Effectiveness examined expression FIVE functional enrichment Functional enrichment analysis GBP1 gene network GeneMANIA Genes global pandemic HERC5 humans identify Ifi44 IFI44L IFIT3 IFIT5 IFN signaling IFN signaling pathway IFN-α/β Immune cell infiltration immune cells Immune escape immune evasion immune system Immunological response Infection infections infiltration Intersection ISG15 KEGG mechanism miRNA molecular mechanism molecular target NLR OAS1 oxidative phosphorylation pathogenic bacteria pathway Patient platform positive correlation PPI network prevalent proliferation promote regulate Regulation Rheumatoid rheumatoid arthritis risk factor ROC curves RSAD2 Rtp4 SARS-CoV-2 SARS-COV-2 infection severe coronavirus disease signaling pathway Staphylococcus Staphylococcus aureus target the SARS-CoV-2 therapeutic viral infection viral replication virus were used YY1
[DOI] 10.3389/fimmu.2022.1013322 PMC 바로가기

The choroid plexus and its role in the pathogenesis of neurological infections

Article

Published on 2022-09-102022-11-15
Journal: Fluids and Barriers of the CNS
[Category] SARS, 치료기술, 치료제,

[키워드] Activation Alter bidirectional Blood–CSF barrier Borrelia Borrelia burgdorferi Brain Cell cells cellular response Central nervous system cerebrospinal fluid changes in chemotaxis choroid Choroid plexus circulating CNS CNS disorder cytokine dendritic cells develop Diseases disorder driving epithelia epithelial epithelial cell function greater highlight homeostasis homing hydrocephalus Immune cell immune cells immune response Immunity immunological Including induce Infection infections Inflammation inflammatory signal John Cunningham virus junction knowledge less macrophages Neuroinflammation neurological pathogen Pathogenesis Pathogens pharmacological intervention promote provide Research SARS-CoV-2 shown T cells target these cell virus ZIKA virus.
[DOI] 10.1186/s12987-022-00372-6 PMC 바로가기

Immunomodulatory Mechanisms of Mesenchymal Stem Cells and Their Potential Clinical Applications

Article

Published on 2022-09-022022-11-16
Journal: International Journal of Molecular Sciences
[Category] 유전자 메커니즘,

[키워드] application Autoimmune disease Cell Characteristics chemokines clinical Clinical applications Contact contribute COVID-19 Cytokines disease Diseases Effect Engineering Factor Growth factors homing immune immune cells immune disorders Immune homeostasis immune response immunomodulation immunomodulatory immunomodulatory effect immunomodulatory property IMPROVE incurable Inflammatory diseases Inflammatory responses maintain mechanism mesenchymal stem cell mesenchymal stem cells (MSCs). MSC MSCs multifunctional Potential regenerative Regulation Secretome shown signaling molecules STEM stem cell systemic lupus erythematosus therapeutic strategy treat
[DOI] 10.3390/ijms231710023 PMC 바로가기